Hovedprojekt våren 2004 Bruk av Wavelets (en relativt ny matematisk metode) innen medisinsk bildebehandling

Wavelets - Fagside

Prosjekter våren 2004 Matematisk behandling av medisinsk bilde-informasjon Ubegrenset sett av oppgaver av alle vanskelighetsgrader (fra ingen matematikk til avansert matematikk) - Bruk av Wavelets til å bestemme blodårekanter fra ultralydbilder. Oppdragsgiver: SINTEF Unimed Ultralyd i Trondheim. - Bruk av Wavelets til å bestemme brystkreftsvulster på tidlig stadium. Oppdragsgiver: Det Norske Radiumhospital i Oslo (DNR). - Bruk av Wavelets til å bestemme benmasse i kroppen. Oppdragsgiver: Sørlandet Sykehus i Kristiansand. - Bruk av Wavelets til å bestemme blodåretykkelse i lever. Oppdragsgiver: Sørlandet Sykehus i Kristiansand. - Bruk av bl.a. Wavelets innen diagnostikk vha IR. Oppdragsgiver: Sørlandet Sykehus i Arendal.

Tittel - Eksempel på oppgavedefinisjon DNR

Internasjonalt samarbeid Resterende sider (på engelsk) er utarbeidet i forbindelse med en invitasjon jeg fikk til en internasjonal matematikk-konferanse i Baltikum høsten 2003 for å holde foredrag om mitt arbeid med bruk av Wavelets (en relativt ny matematisk metode) innen matematisk behandling av medisinsk bildeinformsjon.

IntroductionIntroduction Per Henrik Hogstad Associate Professor Agder University College Faculty of Engineering and Science Dept of Computer Science Grooseveien 36, N-4876 Grimstad, Norway Telephone:

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IntroductionIntroduction Per Henrik Hogstad -Mathematics -Statistics -Physics(Main subject: Theoretical Nuclear Physics) -Computer Science -Programming / Objectorienting -Algorithms and Datastructures -Databases -Digital Image Processing -Supervisor Master Thesis -Research -PHH:Mathem of Wavelets + Computer Application Wavelets/Medicine -Students:Application + TestWavelets/Medicine

ResearchResearch SINTEF Unimed Ultrasound in Trondheim The Norwegian Radiumhospital in Oslo Sørlandet hospitalin Kristiansand / Arendal Mathematics - Computer Science - Medicine

Mathematical Image Operation - Application

Wavelets New mathematical method with many interesting applications Divide a function into parts with frequency and time/position information Signal Processing-Image Processing-Astronomy/Optics/Nuclear Physics Image/Speech recognition-Seismologi-Diff.equations/Discontinuity …

Definition of The Continuous Wavelet Transform CWT The continuous-time wavelet transform (CWT) of f(x) with respect to a wavelet  (x): L 2 (R)

Fourier-transformation of a square wave f(x) square wave (T=2) N=2 N=10 N=1

Fourier transformation

CWT - Time and frequency localization Time Frequency Small a: CWT resolve events closely spaced in time. Large a: CWT resolve events closely spaced in frequency. CWT provides better frequency resolution in the lower end of the frequency spectrum. Wavelet a natural tool in the analysis of signals in which rapidly varying high-frequency components are superimposed on slowly varying low-frequency components (seismic signals, music compositions, pictures…).

Fourier - Wavelet t  a=1/2 a=1 a=2  t Signal Time Inf Fourier Freq Inf Wavelet Time Inf Freq Inf

Filtering / Compression Data compression Remove low W-values Lowpass-filtering Replace W-values by 0 for low a-values Highpass-filtering Replace W-values by 0 for high a-values

Wavelet Transform Morlet Wavelet Fourier/Wavelet Fourier Wavelet

Wavelet Transform Morlet Wavelet Fourier/Wavelet Fourier Wavelet

Wavelet Transform Morlet Wavelet - Visible Oscillation

Wavelet Transform Morlet Wavelet - Non-visible Oscillation [1/2]

Wavelet Transform Morlet Wavelet - Non-visible Oscillation [2/2]

Matcad Program Wavelet Transform

CWT - DWT CWT DWT Binary dilation Dyadic translation Dyadic Wavelets

Analysis /Synthesis Example J=5 Num of Samples: 2 J = 32

Analysis Synthesis J=5 Sampling: 2 5 = 32 j=4j=5j=3j=2j=1j=0

Discrete Wavelet-transformation

Compress 1:50 JPEGWavelet Original

Research The Norwegian Radiumhospital in Oslo -Control of the Linear Accelerator -Databases (patient/employee/activity) -Computations of patientpositions -Mathematical computations of medical image information -Different imageformat (bmp, dicom, …) -Noise Removal -Graylevel manipulation (Histogram, …) -Convolution, Gradientcomputation -Multilayer images -Transformations (Fourier, Wavelet, …) -Mammography -... Wavelet

The Norwegian Radiumhospital Mammography Diameter Relative contrast Number of microcalcifications

The Norwegian Radiumhospital Mammography - Mexican Hat - 2 Dim

The Norwegian Radiumhospital Mammography

Arthritis Measure of bone Morlet External part E/I bone edge

Ultrasound Image - Edge detection SINTEF – Unimed – Ultrasound - Trondheim -Ultrasound Images -Egde Detection -Noise Removal -Egde Sharpening -Edge Detection

Edge Detection Convolution

Edge detection Wavelet Mexican Hat

Edge Detection Wavelet - Scale Energy Wavelet Transform Inv Wavelet Transform Wavelet scale dependent spectrum Energy of the signal A measure of the distribution of energy of the signal f(x) as a function of scale.

Edge detection Wavelet - Max Energy Scale

Edge detection Wavelet - Different Edges

Noise Removal Thresholding HardSoftSemi-Soft

Noise Removal Syntetic Image 45 Wavelets test Original Original+ point spread function + white gaussian noise

Noise Removal Syntetic Image

Noise Removal Ultrasound Image Original Semi-soft Soft

Edge sharpening

Edge detection

Scalogram

Edge detection Scalogram

Edge detection

End